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  1. Context. The study of molecular line emission is crucial to unveil the kinematics and the physical conditions of gas in star-forming regions. We use data from the ALMAGAL survey, which provides an unprecedentedly large statistical sample of high-mass star-forming clumps that helps us to remove bias and reduce noise (e.g., due to source peculiarities, selection, or environmental effects) to determine how well individual molecular species trace continuum emission. Aims. Our aim is to quantify whether individual molecular transitions can be used reliably to derive the physical properties of the bulk of the H2gas, by considering morphological correlations in their overall integrated molecular line emission with the cold dust. We selected transitions of H2CO, CH3OH, DCN, HC3N, CH3CN, CH3OCHO, SO, and SiO and compared them with the 1.38 mm dust continuum emission at different spatial scales in the ALMAGAL sample. We included two transitions of H2CO to understand whether the validity of the results depends on the excitation condition of the selected transition of a molecular species. The ALMAGAL project observed more than 1000 candidate high-mass star-forming clumps in ALMA band 6 at a spatial resolution down to 1000 au. We analyzed a total of 1013 targets that cover all evolutionary stages of the high-mass star formation process and different conditions of clump fragmentation. Methods. For the first time, we used the method called histogram of oriented gradients (HOG) as implemented in the toolastroHOGon a large statistical sample to compare the morphology of integrated line emission with maps of the 1.38 mm dust continuum emission. For each clump, we defined two masks: the first mask covered the extended more diffuse continuum emission, and the second smaller mask that only contained the compact sources. We selected these two masks to study whether and how the correlation among the selected molecules changes with the spatial scale of the emission, from extended more diffuse gas in the clumps to denser gas in compact fragments (cores). Moreover, we calculated the Spearman correlation coefficient and compared it with our astroHOG results. Results. Only H2CO, CH3OH, and SO of the molecular species we analyzed show emission on spatial scales that are comparable with the diffuse 1.38 mm dust continuum emission. However, according the HOG method, the median correlation of the emission of each of these species with the continuum is only ~24–29%. In comparison with the dusty dense fragments, these molecular species still have low correlation values that are below 45% on average. The weak morphological correlation suggests that these molecular lines likely trace the clump medium or outer layers around dense fragments on average (in some cases, this might be due to optical depth effects) or also trace the inner parts of outflows at this scale. On the other hand DCN, HC3N, CH3CN3and CH3OCHO are well correlated with the dense dust fragments at above 60%. The lowest correlation is seen with SiO for the extended continuum emission and for compact sources. Moreover, unlike other outflow tracers, in a large fraction of the sources, SiO does not cover the area of the extended continuum emission well. This and the results of the astroHOG analysis reveal that SiO and SO do not trace the same gas, in contrast to what was previously thought. From the comparison of the results of the HOG method and the Spearman correlation coefficient, the HOG method gives much more reliable results than the intensity-based coefficient when the level of similarity of the emission morphology is estimated. 
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    Free, publicly-accessible full text available July 1, 2026
  2. The physical mechanisms behind the fragmentation of high-mass dense clumps into compact star-forming cores and the properties of these cores are fundamental topics that are heavily investigated in current astrophysical research. The ALMAGAL survey provides the opportunity to study this process at an unprecedented level of detail and statistical significance, featuring high-angular resolution 1.38 mm ALMA observations of 1013 massive dense clumps at various Galactic locations. These clumps cover a wide range of distances (~2–8 kpc), masses (~102–104M), surface densities (0.1–10 g cm−2), and evolutionary stages (luminosity over mass ratio indicator of ~0.05 <L/M <450L/M). Here, we present the catalog of compact sources obtained with theCuTExalgorithm from continuum images of the full ALMAGAL clump sample combining ACA-7 m and 12 m ALMA arrays, reaching a uniform high median spatial resolution of ~1400 au (down to ~800 au). We characterize and discuss the revealed fragmentation properties and the photometric and estimated physical parameters of the core population. The ALMAGAL compact source catalog includes 6348 cores detected in 844 clumps (83% of the total), with a number of cores per clump between 1 and 49 (median of 5). The estimated core diameters are mostly within ~800–3000 au (median of 1700 au). We assigned core temperatures based on theL/Mof the hosting clump, and obtained core masses from 0.002 to 345M(complete above 0.23 M), exhibiting a good correlation with the core radii (M ∝ R2.6). We evaluated the variation in the core mass function (CMF) with evolution as traced by the clumpL/M, finding a clear, robust shift and change in slope among CMFs within subsamples at different stages. This finding suggests that the CMF shape is not constant throughout the star formation process, but rather it builds (and flattens) with evolution, with higher core masses reached at later stages. We found that all cores within a clump grow in mass on average with evolution, while a population of possibly newly formed lower-mass cores is present throughout. The number of cores increases with the core masses, at least until the most massive core reaches ~10M. More generally, our results favor a clump-fed scenario for high-mass star formation, in which cores form as low-mass seeds, and then gain mass while further fragmentation occurs in the clump. 
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    Free, publicly-accessible full text available April 1, 2026
  3. Context.Stars form preferentially in clusters embedded inside massive molecular clouds, many of which contain high-mass stars. Thus, a comprehensive understanding of star formation requires a robust and statistically well-constrained characterization of the formation and early evolution of these high-mass star clusters. To achieve this, we designed the ALMAGAL Large Program that observed 1017 high-mass star-forming regions distributed throughout the Galaxy, sampling different evolutionary stages and environmental conditions. Aims.In this work, we present the acquisition and processing of the ALMAGAL data. The main goal is to set up a robust pipeline that generates science-ready products, that is, continuum and spectral cubes for each ALMAGAL field, with a good and uniform quality across the whole sample. Methods.ALMAGAL observations were performed with the Atacama Large Millimeter/submillimeter Array (ALMA). Each field was observed in three different telescope arrays, being sensitive to spatial scales ranging from ≈1000 au up to ≈0.1 pc. The spectral setup allows sensitive (≈0.1 mJy beam−1) imaging of the continuum emission at 219 GHz (or 1.38 mm), and it covers multiple molecular spectral lines observed in four different spectral windows that span about ≈4 GHz in frequency coverage. We have designed a Python-based processing workflow to calibrate and image these observational data. This ALMAGAL pipeline includes an improved continuum determination, suited for line-rich sources; an automatic self-calibration process that reduces phase-noise fluctuations and improves the dynamical range by up to a factor ≈5 in about 15% of the fields; and the combination of data from different telescope arrays to produce science-ready, fully combined images. Results.The final products are a set of uniformly generated continuum images and spectral cubes for each ALMAGAL field, including individual-array and combined-array products. The fully combined products have spatial resolutions in the range 800–2000 au, and mass sensitivities in the range 0.02–0.07M. We also present a first analysis of the spectral line information included in the ALMAGAL setup, and its potential for future scientific studies. As an example, specific spectral lines (e.g., SiO and CH3CN) at ≈1000 au scales resolve the presence of multiple outflows in clusters and will help us to search for disk candidates around massive protostars. Moreover, the broad frequency bands provide information on the chemical richness of the different cluster members, which can be used to study the chemical evolution during the formation process of star clusters. 
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    Free, publicly-accessible full text available April 1, 2026
  4. Context. A large fraction of stars form in clusters containing high-mass stars, which subsequently influences the local and galaxy-wide environment. Aims. Fundamental questions about the physics responsible for fragmenting molecular parsec-scale clumps into cores of a few thousand astronomical units (au) are still open, that only a statistically significant investigation with ALMA is able to address; for instance: the identification of the dominant agents that determine the core demographics, mass, and spatial distribution as a function of the physical properties of the hosting clumps, their evolutionary stage and the different Galactic environments in which they reside. The extent to which fragmentation is driven by clumps dynamics or mass transport in filaments also remains elusive. Methods. With the ALMAGAL project, we observed the 1.38 mm continuum and lines toward more than 1000 dense clumps in our Galaxy, withM≥ 500 M, Σ ≥ 0.1 g cm−2andd≤ 7.5 kiloparsec (kpc). Two different combinations of ALMA Compact Array (ACA) and 12-m array setups were used to deliver a minimum resolution of ∼1000 au over the entire sample distance range. The sample covers all evolutionary stages from infrared dark clouds (IRDCs) to H IIregions from the tip of the Galactic bar to the outskirts of the Galaxy. With a continuum sensitivity of 0.1 mJy, ALMAGAL enables a complete study of the clump-to-core fragmentation process down toM∼ 0.3 Macross the Galaxy. The spectral setup includes several molecular lines to trace the multiscale physics and dynamics of gas, notably CH3CN, H2CO, SiO, CH3OH, DCN, HC3N, and SO, among others. Results. We present an initial overview of the observations and the early science product and results produced in the ALMAGAL Consortium, with a first characterization of the morphological properties of the continuum emission detected above 5σin our fields. We used “perimeter-versus-area” and convex hull-versus-area metrics to classify the different morphologies. We find that more extended and morphologically complex (significantly departing from circular or generally convex) shapes are found toward clumps that are relatively more evolved and have higher surface densities. Conclusions. ALMAGAL is poised to serve as a game-changer for a number of specific issues in star formation: clump-to-core fragmentation processes, demographics of cores, core and clump gas chemistry and dynamics, infall and outflow dynamics, and disk detections. Many of these issues will be covered in the first generation of papers that closely follow on the present publication. 
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    Free, publicly-accessible full text available April 1, 2026
  5. We present the results of a molecular survey of comet 67P/Churyumov-Gerasimenko undertaken with the Institut de RadioAstronomie Millimétrique (IRAM) 30-m radio telescope in November–December 2021, when it had its most favourable apparition in decades. Observations at IRAM 30-m during the 12–16 November period covered 8 GHz bandwidth at 3 mm, 16 GHz at 2 mm, and 60 GHz in the 1 mm window domain. These were completed by snapshots at 1 mm on 12–13 December and a short observation of the H 2 O line at 557 GHz with the Odin sub-millimetre observatory on 17.0 November 2021, and with 18-cm observations of OH with the Nançay radio telescope. Less sensitive observations obtained at a previous perihelion passage on 18–22 September 2015 with IRAM and 9–12 November 2015 with Odin are also presented. The gas outflow velocity, outgassing pattern, and temperature have been accurately constrained by the observations. They are perfectly consistent with those measured in situ with the Rosetta/MIRO sub-millimetre instrument in 2015. In particular, the asymmetry of the line is well represented by a jet concentrating three-quarters of the outgassing in about π steradians. We derived abundances relative to water for seven molecules and significant upper limits for approximately five others. The retrieved abundances were compared to those measured in situ at the previous perihelion with Rosetta. While those of HCN, CH 3 OH, and HNCO are comparable, 67P is found to be depleted in H 2 S and relatively normal in CS (H 2 S/CS ≈ 3) in strong contradiction with the Rosetta/ROSINA mass spectrometer measurement of the H 2 S/CS 2 (≈100) abundance ratio. While the formaldehyde total abundance found with IRAM 30-m when assuming it to be mostly produced by a distributed source (Haser parent scale length ≈8000 km) is similar to the one derived by Rosetta/ROSINA, we find that the formaldehyde coming from the nucleus is one order of magnitude less abundant than measured in situ by Rosetta/ROSINA. 
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  6. Abstract Gas-phase molecules in cometary atmospheres (comae) originate primarily from (1) outgassing by the nucleus, (2) sublimation of icy grains in the near-nucleus coma, and (3) coma (photo)chemical processes. However, the majority of cometary gases observed at radio wavelengths have yet to be mapped, so their production/release mechanisms remain uncertain. Here we present observations of six molecular species toward comet 46P/Wirtanen, obtained using the Atacama Large Millimeter/submillimeter Array during the comet’s unusually close (∼0.1 au) approach to Earth in 2018 December. Interferometric maps of HCN, CH3OH, CH3CN, H2CO, CS, and HNC were obtained at an unprecedented sky-projected spatial resolution of up to 25 km, enabling the nucleus and coma sources of these molecules to be accurately quantified. The HCN, CH3OH, and CH3CN spatial distributions are consistent with production by direct outgassing from (or very close to) the nucleus, with a significant proportion of the observed CH3OH originating from sublimation of icy grains in the near-nucleus coma (at a scale lengthLp= 36 ± 7 km). On the other hand, H2CO, CS, and HNC originate primarily from distributed coma sources (withLpvalues in the range 550–16,000 km), the identities of which remain to be established. The HCN, CH3OH, and HNC abundances in 46P are consistent with the average values previously observed in comets, whereas the H2CO, CH3CN, and CS abundances are relatively low. 
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  7. null (Ed.)
    We present the results of millimetre-wave spectroscopic observations and spectral surveys of the following short-period comets: 21P/Giacobini-Zinner in September 2018, 41P/Tuttle-Giacobini-Kresák in April 2017, and 64P/Swift-Gehrels and 38P/Stephan-Oterma in December 2018, carried out with the Institut de RadioAstronomie Millimétrique (IRAM) 30-m radio telescope at wavelengths between 1 and 3 mm. Comet 21P was also observed in November 1998 with the IRAM 30-m, James Clerk Maxwell Telescope, and the Caltech submillimeter Observatory radio telescopes at wavelengths from 0.8 to 3 mm. The abundances of the following molecules have been determined in those comets: HCN, CH 3 OH, CS, H 2 CO, CH 3 CN, and H 2 S in comet 21P; HCN and CH 3 OH in 41P; HCN, CH 3 OH, and CS in 64P; and CH 3 OH in 38P. The last three comets, classified as carbon-chain typical from visible spectro-photometry, are relatively rich in methanol (3.5–5% relative to water). On the other hand, comet 21P, classified as carbon-chain depleted, shows abundances relative to water which are low for methanol (1.7%), very low for H 2 S (0.1%), and also relatively low for H 2 CO (0.16%) and CO (<2.5%). Observations of comet 21P do not show any change in activity and composition between the 1998 and 2018 perihelions. Sensitive upper limits on the abundances of other molecules such as CO, HNCO, HNC, or SO are also reported for these comets. 
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  8. null (Ed.)
    We present the results of a molecular survey of comet 46P/Wirtanen undertaken with the IRAM 30-m and NOEMA radio telescopes in December 2018. Observations at IRAM 30-m during the 12–18 December period comprise a 2 mm spectral survey covering 25 GHz and a 1 mm survey covering 62 GHz. The gas outflow velocity and kinetic temperature have been accurately constrained by the observations. We derive abundances of 11 molecules, some being identified remotely for the first time in a Jupiter-family comet, including complex organic molecules such as formamide, ethylene glycol, acetaldehyde, or ethanol. Sensitive upper limits on the abundances of 24 other molecules are obtained. The comet is found to be relatively rich in methanol (3.4% relative to water), but relatively depleted in CO, CS, HNC, HNCO, and HCOOH. 
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